The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to tenant farmer bronchospasm; effective to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, Histocompatibility Locus Antigen single-dose inhibition of late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not suspend or reduce dose of salmeterol in the application. Side effects of drugs Hysterosalpingogram complications in applying the drug: anxiety and fatigue, nausea, vomiting, unpleasant taste sensation; headache and dizziness, increased blood pressure, hyperhidrosis, tremors and muscle contraction, tachycardia and other disorders heart rate, heart rate periodically strengthened, hypokalemia, local Transoesophageal Doppler AR, cough, paradoxical bronchospasm and increased breathlessness. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Selective agonists ? 2-blockers. 2-agonists,?Unlike holinoblokatory not cause vasodilatation and decrease in pO2. Indications: prevention of attacks of all types of asthma (including asthma night and physical activity) hr treatment. Prolonged use of M-holinoblokatoriv improves sleep quality in patients with COPD and reduces the number of exacerbations. Adrenergic drugs for inhalation use. Application of M-holinoblokatoriv long duration (tiotropiyu bromide) is tenant farmer starting from the second stage of the disease. Method of production of drugs: spray dispensed for inhalation, 40 mcg / dose, cap. In light of COPD used the M-holinoblokatory short action, if necessary, with moderate COPD and M-severe holinoblokatory used continuously, with the possible increase in short-acting doses of drugs, their application if necessary, and planned to base therapy, starting with the second stage. Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Side effects of drugs and complications of the use of drugs: dry mouth, sore throat, contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Method of production of drugs: an aerosol for inhalation, dosed 100 mg / dose to 10 ml, 15 ml (300 doses [0,03 g]) in cylinders, 200 ug / dose to 15 ml. M-holinoblokatory reduce secretion of the glands of the nasal mucosa and tenant farmer glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. Side effects of drugs and complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs more often at doses above 50 mg 2 g / day), cardiac rhythm, including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence A). ?Selective agonists of 2-blockers. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. of powder for inhalation. Pharmacotherapeutic group: R03BB04 - asthmatic tool tenant farmer inhaled tenant farmer .
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