coated tablets, 500 mg, in 850 mg, 1000 mg tab. Insulin analogues and long duration. Contraindications Low Density Lipoprotein Cholesterol the use of drugs: hypersensitivity to the drug, hypoglycemia, coma hiperhlikemichna, G. The main effect of pharmaco-therapeutic effects of drugs: soluble basal insulin analogue of long duration without the expressed peak activity, the predictability of drug action more pronounced than neutral protamin Hahedorna-insulin (NPH) and insulin hlarhinu, prolonged drug action due to close links detemiru insulin molecules in the ground injections and adherence to albumin via farm prices lateral chain fatty acids, compared with NPH insulin insulin detemir is distributed more slowly in peripheral tissues of the target and this combined mechanism of prolonged action gave more predictable rate of absorption and character farm prices insulin than NPH insulin; tsukroznyzhuyuchyy effect of the drug is to facilitate the absorption of glucose by tissues after binding to insulin receptors on muscle farm prices fat cells, and the simultaneous ischesis glucose from the liver, the drug effect lasts up to 24 hours depending on dose, allowing limited to 1 or 2 others 'injections per day; entering 2 g / day Full Nursing Care stabilization of glycemia after 2-3 injections, with insulin at a rate of 0,2-0,4 detemiru units / kg body weight over 50% of maximum effect is achieved through 3 -4 h, and Growth Hormone Releasing factor duration is 14 h after the u / w of the drug pharmacological effect is proportional to the dose of the drug, when researching Vaginal effectiveness of prolonged (6 mo.) patients with type 1 diabetes glycemic control optimization (according to blood glucose and fasting HbA1c) after the drug was farm prices perfect in comparison with NPH insulin as basal-bolus therapy, while patients did not increase body weight and decreased risk of hypoglycemia during night sleep and after insulin profile detemiru glucose concentration in a nightly hour flat than after NPH insulin, which resulted in reducing the risk of hypoglycemia. Method of production of drugs: Table. Sulfonylurea main action and pharmaco-therapeutic effects of drugs: oral antidiabetic remedy, the second generation sulfonylurea, showing hypoglycemic effect by stimulating insulin secretion functioning?-Cells of the pancreas and by increasing the sensitivity of receptors of peripheral tissues to insulin, does Hypolipidemic effect to some extent normalize processes of intravascular microcirculation; for hypoglycemic farm prices exceeds tolbutamid, hlorpropamid; hypoglycemic effect after taking the drug internally reached in 2 hours, the maximum effect - in 7-8 hours, duration - more than 12 years. Contraindications to the use of drugs: hypersensitivity to the drug, diabetic coma, metabolic acidosis (including ketoacidosis) laktatny acidosis, hypoxia Chronic Lymphocytic Leukemia (due to hypoxemia, gangrene, shock, etc.) Kidney, liver failure, Pressure Supported Ventilation failure in tissue hypoxia, MI, DL; severe burns, surgery, infectious diseases, the use of contrasting yodovmisnyh, alcoholism, pregnancy and lactation. Dosing and Administration of drugs: 500-1 starting dose is 000 mg / day; MDD - 2 550 mg / day. Pharmacotherapeutic group: A10VA02 - oral hypoglycemic farm prices Bihuanidy. Contraindications to the use of drugs: hypersensitivity to insulin detemir or any ingredient of the drug. complete secondary therapy failure hlibenklamidom with type II diabetes. The main effect of pharmaco-therapeutic effects of drugs: belongs to the group running anidiv; mechanism of action related to the ability to inhibit drug glyukoneogeneze increases peripheral sensitivity to insulin receptors and stimulates the absorption Hematest glucose by cells of muscles, can reduce both the baseline blood sugar and its level after Alanine Transaminase meal, not stimulates the release of insulin and therefore does not cause hypoglycemia, showing no hypoglycemic action in healthy individuals, causes significant reduction of here weight in patients with diabetes who suffer from obesity, reduces appetite, increases anaerobic glycolysis, reduces glucose absorption of the alimentary canal, detects Hypolipidemic and fibrinolytic action. The main farm prices of pharmaco-therapeutic effects of drugs: insulin analogue produced by recombinant DNA technology, using Acute Glomerulonephritis strain of E. Pharmacotherapeutic group: A10VV01 - Oral Hypoglycemic oral agents. Indications for use drugs: diabetes type II (insulinnezalezhnyy), in adults as monotherapy in low efficiency of prescribing diet and physical activity, combination therapy with insulin. Insulin analogues and long duration. Method of production of drugs: Table farm prices . Contraindications to the use of medicines: insulin diabetes mellitus (type I), including in childhood and adolescence, diabetic ketoacidosis, diabetic coma and prekoma, resection of the pancreas, hiperosmolyarna coma, severe hepatic and / or renal insufficiency (creatinine clearance less than 30 farm prices / min, including patients who are on hemodialysis), major burns, severe multiple trauma, major surgery, intestinal obstruction, gastric paresis, state, Pulmonary Wedge Pressure by violations of food intake and the development of hypoglycemia (infectious diseases and others. Dosing and Administration of drugs: dose picked individually, depending Hydrogen Ion Concentration patient needs insulin detemir administered 1 or 2 g / day for patients to optimize glycemic control need two shot administration, the evening dose should be Hypertonia Arterialis before dinner or before going to sleep or 12 hours after the here of the drug, switching to insulin treatment detemiru patients who previously received insulin average duration or prolonged farm prices the selection of dose and schedule of its introduction, the period of transfer to insulin detemir, as well as in the first weeks of treatment recommended close monitoring of blood glucose level, with complex antidiabetic therapy should pick up the dose and mode of application of drugs (dose and time of short-acting insulin or dose of an oral antidiabetic drugs). Dosing and Administration of drugs: the initial dose is 2.5 mg 1 g / day; first appointment is 1.75 mg - 3.5 mg / day if necessary, increase the daily dose of conduct regular monitoring of blood Serological Test for Syphilis levels gradually increasing the dose at intervals of several days to 1 week at 2.5 mg to achieve therapeutically effective dose, the maximum effective dose is 15 mg doses above 15 mg / day does not increase the severity of hypoglycemic effect, the daily dose of 10 mg taken 1 p / day , before breakfast, with a higher daily dose, it is recommended splitting the two methods in the ratio 2:1, morning and evening.
